Peptides
Melanotan 1: The Ultimate Guide to Boost Tanning
Melanotan 1 (MT-1), also known as afamelanotide, is a synthetic peptide that mimics your body's natural alpha-melanocyte-stimulating hormone (alpha-MSH). Unlike its more aggressive cousin Melanotan 2, MT-1 is more receptor-selective and has achieved regulatory approval in Europe for treating the rare light-sensitivity disorder erythropoietic protoporphyria (EPP).
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Quick Facts
| Quick Facts | Details |
|---|---|
| Also Known As | Afamelanotide, Scenesse (brand name) |
| Compound Type | Synthetic alpha-MSH analog (melanocortin peptide) |
| Primary Mechanism | MC1R activation on melanocytes |
| Key Effects | Photoprotective tanning, anti-inflammatory, potential metabolic and mood benefits |
| Administration | Subcutaneous injection (research use) / implant (approved form) |
| FDA Status | Not FDA-approved; EU-approved (Scenesse) for EPP |
| Research Stage | Clinical trials for EPP; limited human data for other applications |
| Risk Level | Low-Moderate compared to MT-2; medical supervision recommended |
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Dosage
Research-use protocol (reconstructed from the values stated in the source).
| Phase | Dose | Frequency |
|---|---|---|
| Loading (Weeks 1–4) | 250 mcg | Daily |
| Weeks 5–8 | 500 mcg | Daily |
| Maintenance (Week 9+) | 500–1000 mcg | 1–2× per week |
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Approved Form (Scenesse)
The approved Scenesse form is administered as a 16 mg subcutaneous implant every 60 days for EPP patients.
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Stacking
- MT-1 + PT-141
- MT-1 + Ipamorelin / Tesamorelin
- MT-1 + ketogenic diet / intermittent fasting
This profile is being expanded — additional sections from the source are still being added.
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